Antiretrovirals, Fractures, and Osteonecrosis in a Large International HIV Cohort.
Identifieur interne : 001178 ( Main/Exploration ); précédent : 001177; suivant : 001179Antiretrovirals, Fractures, and Osteonecrosis in a Large International HIV Cohort.
Auteurs : Álvaro H. Borges ; Jennifer Hoy [Australie] ; Eric Florence [Belgique] ; Dalibor Sedlacek [République tchèque] ; Hans-Jürgen Stellbrink [Allemagne] ; Vilma Uzdaviniene [Lituanie] ; Janez Tomazic [Slovénie] ; Panagiotis Gargalianos-Kakolyris [Grèce] ; Patrick Schmid [Suisse] ; Chloe Orkin [Royaume-Uni] ; Court Pedersen [Danemark] ; Clifford Leen [Royaume-Uni] ; Christian Pradier [France] ; Fiona Mulcahy [Irlande (pays)] ; Anna Lisa Ridolfo [Italie] ; Therese Staub ; Fernando Maltez [Portugal] ; Rainer Weber [Suisse] ; Leo Flamholc [Suède] ; Galina Kyselyova ; Jens D. Lundgren ; Amanda Mocroft [Royaume-Uni]Source :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2017.
Abstract
Antiretrovirals (ARVs) affect bone density and turnover, but their effect on risk of fractures and osteonecrosis of the femoral head is less understood. We investigated if exposure to ARVs increases the risk of both bone outcomes.
DOI: 10.1093/cid/cix167
PubMed: 28329090
Affiliations:
- Allemagne, Australie, Belgique, Danemark, France, Grèce, Irlande (pays), Italie, Lituanie, Portugal, Royaume-Uni, République tchèque, Slovénie, Suisse, Suède
- Angleterre, Attique (région), Grand Londres, Hambourg, Lombardie, Provence-Alpes-Côte d'Azur, Victoria (État), Écosse
- Athènes, Hambourg, Londres, Melbourne, Milan, Nice, Édimbourg
- University College de Londres
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Sacco, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Ospedale L. 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Borges</name><affiliation><nlm:affiliation>Centre of Excellence for Health, Immunity and Infections (CHIP), Department of Infectious Diseases, Rigshospitalet, and.</nlm:affiliation><wicri:noCountry code="subField">and</wicri:noCountry></affiliation></author><author><name sortKey="Hoy, Jennifer" sort="Hoy, Jennifer" uniqKey="Hoy J" first="Jennifer" last="Hoy">Jennifer Hoy</name><affiliation wicri:level="3"><nlm:affiliation>Department of Infectious Diseases, The Alfred Hospital and Monash University, Melbourne, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Infectious Diseases, The Alfred Hospital and Monash University, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Florence, Eric" sort="Florence, Eric" uniqKey="Florence E" first="Eric" last="Florence">Eric Florence</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Tropical Medicine, Antwerp, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Institute of Tropical Medicine, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation></author><author><name sortKey="Sedlacek, Dalibor" sort="Sedlacek, Dalibor" uniqKey="Sedlacek D" first="Dalibor" last="Sedlacek">Dalibor Sedlacek</name><affiliation wicri:level="1"><nlm:affiliation>Charles University Hospital Plzen, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Charles University Hospital Plzen</wicri:regionArea></affiliation></author><author><name sortKey="Stellbrink, Hans Jurgen" sort="Stellbrink, Hans Jurgen" uniqKey="Stellbrink H" first="Hans-Jürgen" last="Stellbrink">Hans-Jürgen Stellbrink</name><affiliation wicri:level="3"><nlm:affiliation>Infektionsmedizinisches Centrum Hamburg (ICH) Study Center, Innere Medizin, Hamburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Infektionsmedizinisches Centrum Hamburg (ICH) Study Center, Innere Medizin, Hamburg</wicri:regionArea><placeName><settlement type="city">Hambourg</settlement><region type="land" nuts="2">Hambourg</region></placeName></affiliation></author><author><name sortKey="Uzdaviniene, Vilma" sort="Uzdaviniene, Vilma" uniqKey="Uzdaviniene V" first="Vilma" last="Uzdaviniene">Vilma Uzdaviniene</name><affiliation wicri:level="1"><nlm:affiliation>Vilnius University Hospital Santariskiu Klinikos, Vilnius, Lithuania.</nlm:affiliation><country xml:lang="fr">Lituanie</country><wicri:regionArea>Vilnius University Hospital Santariskiu Klinikos, Vilnius</wicri:regionArea><wicri:noRegion>Vilnius</wicri:noRegion></affiliation></author><author><name sortKey="Tomazic, Janez" sort="Tomazic, Janez" uniqKey="Tomazic J" first="Janez" last="Tomazic">Janez Tomazic</name><affiliation wicri:level="1"><nlm:affiliation>University Medical Centre Ljubljana, Clinic of Infectious Diseases Ljubljana, Medical Faculty, University of Ljubljana, Slovenia.</nlm:affiliation><country xml:lang="fr">Slovénie</country><wicri:regionArea>University Medical Centre Ljubljana, Clinic of Infectious Diseases Ljubljana, Medical Faculty, University of Ljubljana</wicri:regionArea><wicri:noRegion>University of Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Gargalianos Kakolyris, Panagiotis" sort="Gargalianos Kakolyris, Panagiotis" uniqKey="Gargalianos Kakolyris P" first="Panagiotis" last="Gargalianos-Kakolyris">Panagiotis Gargalianos-Kakolyris</name><affiliation wicri:level="3"><nlm:affiliation>The General Hospital of Athens "G. Gennimatas" First Department Of Medicine - Infectious Diseases Unit, Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>The General Hospital of Athens "G. Gennimatas" First Department Of Medicine - Infectious Diseases Unit, Athens</wicri:regionArea><placeName><settlement type="city">Athènes</settlement><region nuts="2" type="region">Attique (région)</region></placeName></affiliation></author><author><name sortKey="Schmid, Patrick" sort="Schmid, Patrick" uniqKey="Schmid P" first="Patrick" last="Schmid">Patrick Schmid</name><affiliation wicri:level="1"><nlm:affiliation>Division of Infectious Diseases, Cantonal Hospital St. Gallen, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Division of Infectious Diseases, Cantonal Hospital St. Gallen</wicri:regionArea><wicri:noRegion>Cantonal Hospital St. Gallen</wicri:noRegion></affiliation></author><author><name sortKey="Orkin, Chloe" sort="Orkin, Chloe" uniqKey="Orkin C" first="Chloe" last="Orkin">Chloe Orkin</name><affiliation wicri:level="3"><nlm:affiliation>Barts and The Royal London Hospital NHS Trust, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Barts and The Royal London Hospital NHS Trust, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Pedersen, Court" sort="Pedersen, Court" uniqKey="Pedersen C" first="Court" last="Pedersen">Court Pedersen</name><affiliation wicri:level="1"><nlm:affiliation>Odense Universitetshospital, Forskningsenheden, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Odense Universitetshospital, Forskningsenheden</wicri:regionArea><wicri:noRegion>Forskningsenheden</wicri:noRegion></affiliation></author><author><name sortKey="Leen, Clifford" sort="Leen, Clifford" uniqKey="Leen C" first="Clifford" last="Leen">Clifford Leen</name><affiliation wicri:level="3"><nlm:affiliation>Western General Hospital, Edinburgh, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Western General Hospital, Edinburgh</wicri:regionArea><placeName><settlement type="city">Édimbourg</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Pradier, Christian" sort="Pradier, Christian" uniqKey="Pradier C" first="Christian" last="Pradier">Christian Pradier</name><affiliation wicri:level="3"><nlm:affiliation>CHU Nice Hopital de l' Archet 1, Nice, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>CHU Nice Hopital de l' Archet 1, Nice</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Nice</settlement></placeName></affiliation></author><author><name sortKey="Mulcahy, Fiona" sort="Mulcahy, Fiona" uniqKey="Mulcahy F" first="Fiona" last="Mulcahy">Fiona Mulcahy</name><affiliation wicri:level="1"><nlm:affiliation>St. James' Hospital, Dublin, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>St. James' Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Ridolfo, Anna Lisa" sort="Ridolfo, Anna Lisa" uniqKey="Ridolfo A" first="Anna Lisa" last="Ridolfo">Anna Lisa Ridolfo</name><affiliation wicri:level="3"><nlm:affiliation>Ospedale L. Sacco, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Ospedale L. Sacco, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Staub, Therese" sort="Staub, Therese" uniqKey="Staub T" first="Therese" last="Staub">Therese Staub</name><affiliation><nlm:affiliation>Centre Hospitalier de Luxembourg, Luxemborg.</nlm:affiliation><wicri:noCountry code="subField">Luxemborg</wicri:noCountry></affiliation></author><author><name sortKey="Maltez, Fernando" sort="Maltez, Fernando" uniqKey="Maltez F" first="Fernando" last="Maltez">Fernando Maltez</name><affiliation wicri:level="1"><nlm:affiliation>Hospital Curry Cabral, Lisbon, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Hospital Curry Cabral, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Weber, Rainer" sort="Weber, Rainer" uniqKey="Weber R" first="Rainer" last="Weber">Rainer Weber</name><affiliation wicri:level="1"><nlm:affiliation>University Hospital Zürich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>University Hospital Zürich</wicri:regionArea></affiliation></author><author><name sortKey="Flamholc, Leo" sort="Flamholc, Leo" uniqKey="Flamholc L" first="Leo" last="Flamholc">Leo Flamholc</name><affiliation wicri:level="1"><nlm:affiliation>Skåne University Hospital, Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Skåne University Hospital, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Kyselyova, Galina" sort="Kyselyova, Galina" uniqKey="Kyselyova G" first="Galina" last="Kyselyova">Galina Kyselyova</name><affiliation><nlm:affiliation>Crimean Republican AIDS Centre, Simferopol, Ukraine; and.</nlm:affiliation><wicri:noCountry code="subField">Ukraine; and</wicri:noCountry></affiliation></author><author><name sortKey="Lundgren, Jens D" sort="Lundgren, Jens D" uniqKey="Lundgren J" first="Jens D" last="Lundgren">Jens D. Lundgren</name><affiliation><nlm:affiliation>Centre of Excellence for Health, Immunity and Infections (CHIP), Department of Infectious Diseases, Rigshospitalet, and.</nlm:affiliation><wicri:noCountry code="subField">and</wicri:noCountry></affiliation></author><author><name sortKey="Mocroft, Amanda" sort="Mocroft, Amanda" uniqKey="Mocroft A" first="Amanda" last="Mocroft">Amanda Mocroft</name><affiliation wicri:level="4"><nlm:affiliation>Department of Infection and Population Health, University College London, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Infection and Population Health, University College London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName type="university">University College de Londres</orgName></affiliation></author></analytic><series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title><idno type="eISSN">1537-6591</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Antiretrovirals (ARVs) affect bone density and turnover, but their effect on risk of fractures and osteonecrosis of the femoral head is less understood. We investigated if exposure to ARVs increases the risk of both bone outcomes.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Danemark</li><li>France</li><li>Grèce</li><li>Irlande (pays)</li><li>Italie</li><li>Lituanie</li><li>Portugal</li><li>Royaume-Uni</li><li>République tchèque</li><li>Slovénie</li><li>Suisse</li><li>Suède</li></country><region><li>Angleterre</li><li>Attique (région)</li><li>Grand Londres</li><li>Hambourg</li><li>Lombardie</li><li>Provence-Alpes-Côte d'Azur</li><li>Victoria (État)</li><li>Écosse</li></region><settlement><li>Athènes</li><li>Hambourg</li><li>Londres</li><li>Melbourne</li><li>Milan</li><li>Nice</li><li>Édimbourg</li></settlement><orgName><li>University College de Londres</li></orgName></list><tree><noCountry><name sortKey="Borges, Alvaro H" sort="Borges, Alvaro H" uniqKey="Borges A" first="Álvaro H" last="Borges">Álvaro H. Borges</name><name sortKey="Kyselyova, Galina" sort="Kyselyova, Galina" uniqKey="Kyselyova G" first="Galina" last="Kyselyova">Galina Kyselyova</name><name sortKey="Lundgren, Jens D" sort="Lundgren, Jens D" uniqKey="Lundgren J" first="Jens D" last="Lundgren">Jens D. Lundgren</name><name sortKey="Staub, Therese" sort="Staub, Therese" uniqKey="Staub T" first="Therese" last="Staub">Therese Staub</name></noCountry><country name="Australie"><region name="Victoria (État)"><name sortKey="Hoy, Jennifer" sort="Hoy, Jennifer" uniqKey="Hoy J" first="Jennifer" last="Hoy">Jennifer Hoy</name></region></country><country name="Belgique"><noRegion><name sortKey="Florence, Eric" sort="Florence, Eric" uniqKey="Florence E" first="Eric" last="Florence">Eric Florence</name></noRegion></country><country name="République tchèque"><noRegion><name sortKey="Sedlacek, Dalibor" sort="Sedlacek, Dalibor" uniqKey="Sedlacek D" first="Dalibor" last="Sedlacek">Dalibor Sedlacek</name></noRegion></country><country name="Allemagne"><region name="Hambourg"><name sortKey="Stellbrink, Hans Jurgen" sort="Stellbrink, Hans Jurgen" uniqKey="Stellbrink H" first="Hans-Jürgen" last="Stellbrink">Hans-Jürgen Stellbrink</name></region></country><country name="Lituanie"><noRegion><name sortKey="Uzdaviniene, Vilma" sort="Uzdaviniene, Vilma" uniqKey="Uzdaviniene V" first="Vilma" last="Uzdaviniene">Vilma Uzdaviniene</name></noRegion></country><country name="Slovénie"><noRegion><name sortKey="Tomazic, Janez" sort="Tomazic, Janez" uniqKey="Tomazic J" first="Janez" last="Tomazic">Janez Tomazic</name></noRegion></country><country name="Grèce"><region name="Attique (région)"><name sortKey="Gargalianos Kakolyris, Panagiotis" sort="Gargalianos Kakolyris, Panagiotis" uniqKey="Gargalianos Kakolyris P" first="Panagiotis" last="Gargalianos-Kakolyris">Panagiotis Gargalianos-Kakolyris</name></region></country><country name="Suisse"><noRegion><name sortKey="Schmid, Patrick" sort="Schmid, Patrick" uniqKey="Schmid P" first="Patrick" last="Schmid">Patrick Schmid</name></noRegion><name sortKey="Weber, Rainer" sort="Weber, Rainer" uniqKey="Weber R" first="Rainer" last="Weber">Rainer Weber</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Orkin, Chloe" sort="Orkin, Chloe" uniqKey="Orkin C" first="Chloe" last="Orkin">Chloe Orkin</name></region><name sortKey="Leen, Clifford" sort="Leen, Clifford" uniqKey="Leen C" first="Clifford" last="Leen">Clifford Leen</name><name sortKey="Mocroft, Amanda" sort="Mocroft, Amanda" uniqKey="Mocroft A" first="Amanda" last="Mocroft">Amanda Mocroft</name></country><country name="Danemark"><noRegion><name sortKey="Pedersen, Court" sort="Pedersen, Court" uniqKey="Pedersen C" first="Court" last="Pedersen">Court Pedersen</name></noRegion></country><country name="France"><region name="Provence-Alpes-Côte d'Azur"><name sortKey="Pradier, Christian" sort="Pradier, Christian" uniqKey="Pradier C" first="Christian" last="Pradier">Christian Pradier</name></region></country><country name="Irlande (pays)"><noRegion><name sortKey="Mulcahy, Fiona" sort="Mulcahy, Fiona" uniqKey="Mulcahy F" first="Fiona" last="Mulcahy">Fiona Mulcahy</name></noRegion></country><country name="Italie"><region name="Lombardie"><name sortKey="Ridolfo, Anna Lisa" sort="Ridolfo, Anna Lisa" uniqKey="Ridolfo A" first="Anna Lisa" last="Ridolfo">Anna Lisa Ridolfo</name></region></country><country name="Portugal"><noRegion><name sortKey="Maltez, Fernando" sort="Maltez, Fernando" uniqKey="Maltez F" first="Fernando" last="Maltez">Fernando Maltez</name></noRegion></country><country name="Suède"><noRegion><name sortKey="Flamholc, Leo" sort="Flamholc, Leo" uniqKey="Flamholc L" first="Leo" last="Flamholc">Leo Flamholc</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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